Recombinant Human beta-Nerve Growth Factor/beta-NGF Protein (with pro peptide)
Cat# MBS2557161-5x0,05mg
Size : 5x0.05mg
Brand : MyBiosource
Contact local distributor :
Phone : +1 850 650 7790
Beta-Nerve Growth Factor/Beta-NGF (beta-NGF) Human Recombinant Protein
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2557161Protein Construction: Recombinant Human pro-Nerve Growth Factor is produced by our E Coli expression system and the target gene encoding Glu19-Ala241 is expressed.Background: The precursor form of the nerve growth factor (proNGF) like its mature form is… More details
Product Overview
Online Datasheet in PDFProduct Name
beta-Nerve Growth Factor/beta-NGF, Recombinant Protein
Full Product Name
Recombinant Human beta-Nerve Growth Factor/beta-NGF Protein (with pro peptide)
Product Gene Name
beta-NGF recombinant protein
Product Synonym Names
Beta-Nerve Growth Factor; Beta-NGF; NGF; NGFB
Sequence
Glu19-Ala2 41
Host
E Coli
Form/Format
Lyophilized from a 0.2 mum filtered solution of 20mM PB, 250mM NaCl, pH 7.2.
Purity/Purification
>95% as determined by reducing SDS-PAGE.
Preparation and Storage
Lyophilized protein should be stored at < -20 degree C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.
Other Notes
Small volumes of beta-NGF recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for beta-NGF purchase
MBS2557161 is a recombinant protein targeting beta-NGF. Also known as Recombinant Human beta-Nerve Growth Factor/beta-NGF Protein (with pro peptide). Host: E Coli.
Additional Details
NCBI/Uniprot data below describe general gene information for beta-NGF. It may not necessarily be applicable to this product.
NCBI Official Full Name
Beta-nerve growth factor
NCBI Official Synonym Full Names
nerve growth factor
NCBI Official Symbol
NGF
NCBI Official Synonym Symbols
NGFB; HSAN5; Beta-NGF
UniProt Protein Name
Beta-nerve growth factor
Protein Family
Beta-nerve growth factor
UniProt Gene Name
NGF
UniProt Synonym Gene Names
NGFB; Beta-NGF
UniProt Entry Name
NGF_HUMAN
NCBI Protein Information
beta-nerve growth factor
NCBI Summary for beta-NGF
This gene is a member of the NGF-beta family and encodes a secreted protein which homodimerizes and is incorporated into a larger complex. This protein has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis. [provided by RefSeq, Jul 2008]
Show more UniProt Comments for beta-NGF
NGF: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Homodimer. Belongs to the NGF-beta family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 1p13.1
Cellular Component: extracellular space; Golgi lumen; cytoplasmic membrane-bound vesicle; extracellular region; endosome
Molecular Function: metalloendopeptidase inhibitor activity; protein binding; nerve growth factor receptor binding; growth factor activity; receptor signaling protein activity
Biological Process: response to nicotine; circadian rhythm; response to peptide hormone stimulus; nerve growth factor receptor signaling pathway; activation of MAPKK activity; positive regulation of apoptosis; adult locomotory behavior; regulation of neuron differentiation; positive regulation of axon extension; response to glucocorticoid stimulus; regulation of neurotransmitter secretion; response to lipopolysaccharide; regulation of caspase activity; sensory perception of pain; regulation of axonogenesis; negative regulation of cell cycle; nerve growth factor processing; response to radiation; cell-cell signaling; small GTPase mediated signal transduction; negative regulation of neuron apoptosis; response to electrical stimulus; inflammatory response; response to drug; positive regulation of neuron maturation; phosphoinositide-mediated signaling; positive regulation of protein amino acid autophosphorylation; positive regulation of nerve growth factor receptor signaling pathway; regulation of release of sequestered calcium ion into cytosol; memory; peripheral nervous system development; neuron apoptosis; induction of apoptosis via death domain receptors; response to mechanical stimulus; phospholipase C activation; response to ozone; Ras protein signal transduction; positive regulation of axonogenesis; positive regulation of transcription factor activity; neurite morphogenesis; transmembrane receptor protein tyrosine kinase signaling pathway; negative regulation of apoptosis
Disease: Neuropathy, Hereditary Sensory And Autonomic, Type V
Show more Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 1p13.1
Cellular Component: extracellular space; Golgi lumen; cytoplasmic membrane-bound vesicle; extracellular region; endosome
Molecular Function: metalloendopeptidase inhibitor activity; protein binding; nerve growth factor receptor binding; growth factor activity; receptor signaling protein activity
Biological Process: response to nicotine; circadian rhythm; response to peptide hormone stimulus; nerve growth factor receptor signaling pathway; activation of MAPKK activity; positive regulation of apoptosis; adult locomotory behavior; regulation of neuron differentiation; positive regulation of axon extension; response to glucocorticoid stimulus; regulation of neurotransmitter secretion; response to lipopolysaccharide; regulation of caspase activity; sensory perception of pain; regulation of axonogenesis; negative regulation of cell cycle; nerve growth factor processing; response to radiation; cell-cell signaling; small GTPase mediated signal transduction; negative regulation of neuron apoptosis; response to electrical stimulus; inflammatory response; response to drug; positive regulation of neuron maturation; phosphoinositide-mediated signaling; positive regulation of protein amino acid autophosphorylation; positive regulation of nerve growth factor receptor signaling pathway; regulation of release of sequestered calcium ion into cytosol; memory; peripheral nervous system development; neuron apoptosis; induction of apoptosis via death domain receptors; response to mechanical stimulus; phospholipase C activation; response to ozone; Ras protein signal transduction; positive regulation of axonogenesis; positive regulation of transcription factor activity; neurite morphogenesis; transmembrane receptor protein tyrosine kinase signaling pathway; negative regulation of apoptosis
Disease: Neuropathy, Hereditary Sensory And Autonomic, Type V
Research Articles on beta-NGF
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with beta-NGF recombinant protein
| Reference Product | PubMed Publications |
|---|---|
| NTRK1 recombinant protein | >2022 publications with beta-NGF and NTRK1 |
| NGFR recombinant protein | >240 publications with beta-NGF and NGFR |
| CASP3 recombinant protein | >174 publications with beta-NGF and CASP3 |
| TRPV1 recombinant protein | >93 publications with beta-NGF and TRPV1 |
| SHC1 recombinant protein | >26 publications with beta-NGF and SHC1 |
| PLG recombinant protein | >7 publications with beta-NGF and PLG |
| GIPC1 recombinant protein | >2 publications with beta-NGF and GIPC1 |
| SORCS3 recombinant protein | >1 publications with beta-NGF and SORCS3 |
| MMP7 recombinant protein | >1 publications with beta-NGF and MMP7 |
| SORT1 recombinant protein | >1 publications with beta-NGF and SORT1 |
Pathways associated with beta-NGF recombinant protein
| Products by Pathway | Pathway Diagram |
|---|---|
| ARMS-mediated Activation Pathway antibodies | ARMS-mediated Activation Pathway Diagram |
| Activation Of TRKA Receptors Pathway antibodies | Activation Of TRKA Receptors Pathway Diagram |
| Apoptosis Pathway antibodies | Apoptosis Pathway Diagram |
| Apoptosis Pathway antibodies | Apoptosis Pathway Diagram |
| Axonal Growth Stimulation Pathway antibodies | Axonal Growth Stimulation Pathway Diagram |
| BDNF Signaling Pathway antibodies | BDNF Signaling Pathway Diagram |
| Cell Death Signalling Via NRAGE, NRIF And NADE Pathway antibodies | Cell Death Signalling Via NRAGE, NRIF And NADE Pathway Diagram |
| Ceramide Signalling Pathway antibodies | Ceramide Signalling Pathway Diagram |
| Frs2-mediated Activation Pathway antibodies | Frs2-mediated Activation Pathway Diagram |
| Id Signaling Pathway antibodies | Id Signaling Pathway Diagram |
Diseases associated with beta-NGF recombinant protein
| Disease Name | Pubmed Publications |
|---|---|
| Nervous System Diseases Antibodies | >2194 publications with beta-NGF and Nervous System Diseases |
| Pain Antibodies | >750 publications with beta-NGF and Pain |
| Neurodegenerative Diseases Antibodies | >730 publications with beta-NGF and Neurodegenerative Diseases |
| Inflammation Antibodies | >692 publications with beta-NGF and Inflammation |
| Nerve Degeneration Antibodies | >609 publications with beta-NGF and Nerve Degeneration |
| Peripheral Nervous System Diseases Antibodies | >462 publications with beta-NGF and Peripheral Nervous System Diseases |
| Necrosis Antibodies | >446 publications with beta-NGF and Necrosis |
| Hyperalgesia Antibodies | >316 publications with beta-NGF and Hyperalgesia |
| Heart Diseases Antibodies | >123 publications with beta-NGF and Heart Diseases |
| Neurobehavioral Manifestations Antibodies | >111 publications with beta-NGF and Neurobehavioral Manifestations |
Organs/Tissues associated with beta-NGF recombinant protein
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Muscle Antibodies | >656 publications with beta-NGF and Muscle |
| Embryonic Tissue Antibodies | >610 publications with beta-NGF and Embryonic Tissue |
| Skin Antibodies | >530 publications with beta-NGF and Skin |
| Eye Antibodies | >430 publications with beta-NGF and Eye |
| Lung Antibodies | >174 publications with beta-NGF and Lung |
| Intestine Antibodies | >113 publications with beta-NGF and Intestine |
| Spleen Antibodies | >92 publications with beta-NGF and Spleen |
| Uncharacterized Tissue Antibodies | >1 publications with beta-NGF and Uncharacterized Tissue |