Recombinant Human Melanoma-associated antigen 3 (MAGEA3)
Cat# MBS961973-0,02mg-E
Size : 0.02mg(E-Coli)
Brand : MyBiosource
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Recombinant Human Melanoma-associated antigen 3 (MAGEA3)
Melanoma-Associated Antigen 3 (MAGEA3) Human Recombinant Protein
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS961973This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this… More details
Product Overview
Online Datasheet in PDFProduct Name
Melanoma-associated antigen 3 (MAGEA3), Recombinant Protein
Full Product Name
Recombinant Human Melanoma-associated antigen 3 (MAGEA3)
Product Gene Name
MAGEA3 recombinant protein
Sequence
MPLEQRSQHC KPEEGLEARG EALGLVGAQA PATEEQEAAS SSSTLVEVTL GEVPAAESPD PPQSPQGASS LPTTMNYPLW SQSYEDSSNQ EEEGPSTFPD LESEFQAALS RKVAELVHFL LLKYRAREPV TKAEMLGSVV GNWQYFFPVI FSKASSSLQL VFGIELMEVD PIGHLYIFAT CLGLSYDGLL GDNQIMPKAG LLIIVLAIIA REGDCAPEEK IWEELSVLEV FEGREDSILG DPKKLLTQHF VQENYLEYRQ VPGSDPACYE FLWGPRALVE TSYVKVLHHM VKISGGPHIS YPPLHEWVLR EGEE
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
39.8 kDa
Sequence Positions
1-314. Full Length
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
OMIM
300174
Species
Human
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Other Notes
Small volumes of MAGEA3 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms for MAGEA3 purchase
MBS961973 is a recombinant protein targeting MAGEA3. Also known as Recombinant Human Melanoma-associated antigen 3 (MAGEA3). Host: E Coli or Yeast or Baculovirus or Mammalian Cell.
Additional Details
NCBI/Uniprot data below describe general gene information for MAGEA3. It may not necessarily be applicable to this product.
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
melanoma-associated antigen 3
NCBI Official Synonym Full Names
MAGE family member A3
NCBI Official Symbol
MAGEA3
NCBI Official Synonym Symbols
HIP8; HYPD; CT1.3; MAGE3; MAGEA6
UniProt Protein Name
Melanoma-associated antigen 3
UniProt Synonym Protein Names
Antigen MZ2-D; Cancer/testis antigen 1.3; CT1.3; MAGE-3 antigen
Protein Family
Melanoma-associated antigen
UniProt Gene Name
MAGEA3
UniProt Synonym Gene Names
MAGE3; CT1.3
NCBI Protein Information
melanoma-associated antigen 3
UniProt Comments for MAGEA3
Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.
Show more Research Articles on MAGEA3
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with MAGEA3 recombinant protein
| Reference Product | PubMed Publications |
|---|---|
| HLA-A recombinant protein | >94 publications with MAGEA3 and HLA-A |
| MLANA recombinant protein | >56 publications with MAGEA3 and MLANA |
| GAGE2A recombinant protein | >9 publications with MAGEA3 and GAGE2A |
| TRIM28 recombinant protein | >2 publications with MAGEA3 and TRIM28 |
| SILV recombinant protein | >1 publications with MAGEA3 and SILV |
| BAGE2 recombinant protein | >1 publications with MAGEA3 and BAGE2 |
Diseases associated with MAGEA3 recombinant protein
| Disease Name | Pubmed Publications |
|---|---|
| Melanoma Antibodies | >323 publications with MAGEA3 and Melanoma |
| Carcinoma Antibodies | >138 publications with MAGEA3 and Carcinoma |
| Neoplasm Metastasis Antibodies | >76 publications with MAGEA3 and Neoplasm Metastasis |
| Lung Neoplasms Antibodies | >56 publications with MAGEA3 and Lung Neoplasms |
| Lung Diseases Antibodies | >55 publications with MAGEA3 and Lung Diseases |
| Adenocarcinoma Antibodies | >51 publications with MAGEA3 and Adenocarcinoma |
| Head and Neck Neoplasms Antibodies | >42 publications with MAGEA3 and Head and Neck Neoplasms |
| Carcinoma, Squamous Cell Antibodies | >37 publications with MAGEA3 and Carcinoma, Squamous Cell |
| Carcinoma, Non-Small-Cell Lung Antibodies | >34 publications with MAGEA3 and Carcinoma, Non-Small-Cell Lung |
| Bronchial Neoplasms Antibodies | >32 publications with MAGEA3 and Bronchial Neoplasms |
Organs/Tissues associated with MAGEA3 recombinant protein
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Testis Antibodies | >112 publications with MAGEA3 and Testis |
| Lung Antibodies | >61 publications with MAGEA3 and Lung |
| Skin Antibodies | >55 publications with MAGEA3 and Skin |
| Lymph Node Antibodies | >49 publications with MAGEA3 and Lymph Node |
| Liver Antibodies | >33 publications with MAGEA3 and Liver |
| Bone Antibodies | >14 publications with MAGEA3 and Bone |
| Placenta Antibodies | >12 publications with MAGEA3 and Placenta |
| Brain Antibodies | >11 publications with MAGEA3 and Brain |
| Salivary Gland Antibodies | >3 publications with MAGEA3 and Salivary Gland |
| Prostate Antibodies | >3 publications with MAGEA3 and Prostate |