RelB(Ser573) Polyclonal Antibody, Cy3 Conjugated

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Cat# bs-5692R-Cy3

Size : 100ul

Contact local distributor :

Phone : +1 850 650 7790

Brand : Bioss

Contact local distributor :

Phone : +1 850 650 7790

bs-5692R-Cy3 [Conjugated Primary Antibody]

RelB(Ser573) Polyclonal Antibody, Cy3 Conjugated

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DATASHEET

Host: Rabbit

Target Protein: RelB Ser573

Modification Site: Ser573

Clonality: Polyclonal

Isotype: IgG

Entrez Gene: 5971

Source: KLH conjugated synthetic phosphopeptide derived from human RelB around the phosphorylation site of Ser573

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

The NFKB complex consists of NFKB1 or NFKB2 bound to REL, RELA, or RELB. The NFKB complex is inhibited by I kappa B proteins (NFKBIA, or NFKBIB), which inactivate NF kappa B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I kappa B proteins by kinases (IKBKA, or IKBKB,) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF kappa B complex. For some genes, activation requires NFKB interaction with other transcription factors, such as STAT, AP1 (JUN), and NFAT.

Conjugation: Cy3

Excitation/ Emission: 512,550nm/570,615nm

Size: 100ul

Concentration: 1ug/ul

Applications: WB(1:300-5000)
IF(IHC-P)(1:50-200)
IF(IHC-F)(1:50-200)
IF(ICC)(1:50-200)

Predicted Molecular Weight: 64

Predicted Cross Reactive Species: Human
Mouse
Rat
Dog
Cow
Sheep
Horse
Rabbit
Guinea Pig

For research use only. Not intended for diagnostic or therapeutic use.