RNase H1 Blocking Peptide

Cat# NB-22-77328-250

Size : 250ug

Brand : Neo Biotech

Contact local distributor :


Phone : +1 850 650 7790

General Info

Applications: Immunodepletion/Immunocompetition
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: RNase H1 Blocking Peptide for STJ506221 is synthetically produced from the 1-75 sequence and is suitable for use in western blot applications.
Formulation: Liquid form at 2.5mg/ml concentration in PBS. Up to 5% DMSO can be added. Orders with >1mg can be supplied in lyophilized powder form, or in buffer of choice.
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.

Information

Gene Symbol: RNASEH1
Gene ID: 246243
Uniprot ID: RNH1_HUMAN
Immunogen Region: 1-75
Specificity: This blocking peptide is recommended for use in combination with RNase H1 antibody, STJ506221
Immunogen: Synthetic peptide corresponding to amino acids within region 1-75 on human Rnase H1 protein.

Description

Function Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II.
Peptide Name Ribonuclease H1
Rnase H1
Ribonuclease H Type Ii
Cellular Localisation Cytoplasm
Alternative Peptide Names Ribonuclease H1 protein
Rnase H1 protein
Ribonuclease H Type Ii protein
RNASEH1 protein
RNH1 protein

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance