RNF138 Antibody
Cat# MBS8582380-0,1mL-PE
Size : 0.1mL(PE)
Brand : MyBiosource
Contact local distributor :
Phone : +1 850 650 7790
RNF138 Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8582380MBS8582380 is an antibody targeting RNF138. Also known as RNF138 Antibody. Reactive in Human, Mouse, Rat, Monkey. Host: Rabbit. Rabbit polyclonal antibody to RNF138 More details
Product Overview
Online Datasheet in PDFProduct Name
RNF138, Polyclonal Antibody
Full Product Name
RNF138 Antibody
Product Gene Name
anti-RNF138 antibody
Product Synonym Names
NARF; E3 ubiquitin-protein ligase RNF138; Nemo-like kinase-associated RING finger protein; NLK-associated RING finger protein; hNARF; RING finger protein 138
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Monkey
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of RNF138 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Molecular Weight
28,193 Da
Chromosome Location
Chromosome: 18; NC_000018.9 (29671818..29711524). Location: 18q12.1
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human RNF138. The exact sequence is proprietary.
Product Categories/Family for anti-RNF138 antibody
Primary Antibody
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-RNF138 antibody
Western Blot (WB)
Application Notes for anti-RNF138 antibody
WB: 1:500-1:1000
Other Notes
Small volumes of anti-RNF138 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for RNF138. It may not necessarily be applicable to this product.
NCBI Official Full Name
E3 ubiquitin-protein ligase RNF138 isoform 1
NCBI Official Synonym Full Names
ring finger protein 138, E3 ubiquitin protein ligase
NCBI Official Symbol
RNF138
NCBI Official Synonym Symbols
NARF; HSD-4; STRIN; hNARF
UniProt Protein Name
E3 ubiquitin-protein ligase RNF138
UniProt Synonym Protein Names
Nemo-like kinase-associated RING finger protein; NLK-associated RING finger protein; hNARF; RING finger protein 138
Protein Family
E3 ubiquitin-protein ligase
UniProt Gene Name
RNF138
UniProt Synonym Gene Names
NARF; NLK-associated RING finger protein; hNARF
UniProt Entry Name
RN138_HUMAN
NCBI Protein Information
E3 ubiquitin-protein ligase RNF138; NLK-associated RING finger protein; Nemo-like kinase-associated RING finger protein; nemo-like kinase associated ring finger protein
NCBI Summary for RNF138
The protein encoded by this gene contains a RING finger, a motif present in a variety of functionally distinct proteins and known to be involved in protein-DNA and protein-protein interactions. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Show more UniProt Comments for RNF138
RNF138: E3 ubiquitin-protein ligase. Together with NLK, involved in the ubiquitination and degradation of TCF/LEF. Also exhibits auto-ubiquitination activity in combination with UBE2K. May act as a negative regulator in the Wnt/beta-catenin-mediated signaling pathway. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 6.3.2.-; EC 6.3.2.19; Ligase; Ubiquitin conjugating system; Ubiquitin ligase
Chromosomal Location of Human Ortholog: 18q12.1
Cellular Component: nucleus
Molecular Function: zinc ion binding; protein kinase binding; ligase activity
Biological Process: Wnt receptor signaling pathway; protein ubiquitination
Show more Protein type: EC 6.3.2.-; EC 6.3.2.19; Ligase; Ubiquitin conjugating system; Ubiquitin ligase
Chromosomal Location of Human Ortholog: 18q12.1
Cellular Component: nucleus
Molecular Function: zinc ion binding; protein kinase binding; ligase activity
Biological Process: Wnt receptor signaling pathway; protein ubiquitination
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Pathways associated with anti-RNF138 antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Adaptive Immune System Pathway antibodies | Adaptive Immune System Pathway Diagram |
| Antigen Processing: Ubiquitination & Proteasome Degradation Pathway antibodies | Antigen Processing: Ubiquitination & Proteasome Degradation Pathway Diagram |
| Class I MHC Mediated Antigen Processing & Presentation Pathway antibodies | Class I MHC Mediated Antigen Processing & Presentation Pathway Diagram |
| Immune System Pathway antibodies | Immune System Pathway Diagram |
Diseases associated with anti-RNF138 antibody
| Disease Name | Pubmed Publications |
|---|---|
| Brain Diseases Antibodies | >2 publications with RNF138 and Brain Diseases |
| Neoplasms Antibodies | >2 publications with RNF138 and Neoplasms |
| Hypertension Antibodies | >1 publications with RNF138 and Hypertension |
| Nervous System Diseases Antibodies | >1 publications with RNF138 and Nervous System Diseases |
Organs/Tissues associated with anti-RNF138 antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Brain Antibodies | >3 publications with RNF138 and Brain |
| Prostate Antibodies | >1 publications with RNF138 and Prostate |
| Intestine Antibodies | >1 publications with RNF138 and Intestine |
| Blood Antibodies | >1 publications with RNF138 and Blood |