SCG3 siRNA (Rat)
Cat# MBS826953-30nmol
Size : 30nmol
Brand : MyBiosource
Contact local distributor :
Phone : +1 850 650 7790
SCG3 siRNA – Secretogranin-3 (Rat)
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS826953MBS826953 is an siRNA targeting SCG3. Also known as SCG3 siRNA (Rat). Reactive in Rat. Host: Synthetic. siRNA to inhibit SCG3 expression using RNA interference More details
Product Overview
Online Datasheet in PDFProduct Name
SCG3, siRNA
Full Product Name
SCG3 siRNA (Rat)
Product Gene Name
SCG3 sirna
Product Synonym Names
Secretogranin-3; 1B1075; Secretogranin III; SgIII
Host
Synthetic
Species Reactivity
Rat
Form/Format
Lyophilized powder
Purity/Purification
> 97%
Specificity
SCG3 siRNA (Rat) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Molecular Weight
53,183 Da
Negative Control
siRNA Negative Control (Catalog# MBS8241404) is a non-targeting 21 nt siRNA recommended as a negative control for experiments using targeted siRNA transfection.
Quality Control
Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
Directions for Use
We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
Components
We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of rat SCG3 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
Applications Tested/Suitable for SCG3 sirna
RNA Interference (RNAi)
Other Notes
Small volumes of SCG3 sirna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for SCG3. It may not necessarily be applicable to this product.
NCBI Official Full Name
secretogranin-3
NCBI Official Synonym Full Names
secretogranin III
NCBI Official Symbol
Scg3
NCBI Official Synonym Symbols
SgIII
UniProt Protein Name
Secretogranin-3
UniProt Synonym Protein Names
1B1075; Secretogranin III; SgIII
Protein Family
Secretogranin
UniProt Gene Name
Scg3
UniProt Synonym Gene Names
SgIII
UniProt Entry Name
SCG3_RAT
NCBI Protein Information
secretogranin-3
NCBI Summary for SCG3
component of intracellular dense core vesicles [RGD, Feb 2006]
UniProt Comments for SCG3
SCG3: 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Cellular Component: extracellular region; cytoplasmic vesicle
Molecular Function: protein binding
Protein type: Secreted; Secreted, signal peptide
Cellular Component: extracellular region; cytoplasmic vesicle
Molecular Function: protein binding
Research Articles on SCG3
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with SCG3 sirna
| Reference Product | PubMed Publications |
|---|---|
| Scg2 sirna | >3 publications with SCG3 and Scg2 |
| Chgb sirna | >2 publications with SCG3 and Chgb |
| Chga sirna | >1 publications with SCG3 and Chga |
Pathways associated with SCG3 sirna
| Products by Pathway | Pathway Diagram |
|---|---|
| Hemostasis Pathway antibodies | Hemostasis Pathway Diagram |
| Platelet Activation, Signaling And Aggregation Pathway antibodies | Platelet Activation, Signaling And Aggregation Pathway Diagram |
| Platelet Degranulation Pathway antibodies | Platelet Degranulation Pathway Diagram |
| Response To Elevated Platelet Cytosolic Ca2+ Pathway antibodies | Response To Elevated Platelet Cytosolic Ca2+ Pathway Diagram |
Diseases associated with SCG3 sirna
| Disease Name | Pubmed Publications |
|---|---|
| Liver Neoplasms Antibodies | >1 publications with SCG3 and Liver Neoplasms |
| Gonadal Disorders Antibodies | >1 publications with SCG3 and Gonadal Disorders |
| Neoplasm Metastasis Antibodies | >1 publications with SCG3 and Neoplasm Metastasis |
| Carcinoma, Hepatocellular Antibodies | >1 publications with SCG3 and Carcinoma, Hepatocellular |
| Liver Diseases Antibodies | >1 publications with SCG3 and Liver Diseases |
Organs/Tissues associated with SCG3 sirna
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Brain Antibodies | >3 publications with SCG3 and Brain |
| Nerve Antibodies | >2 publications with SCG3 and Nerve |