SF3B1 Polyclonal Antibody
Cat# RD266583A-120ul
Size : 120ul
Brand : Reddot Biotech
Contact local distributor :
Phone : +1 850 650 7790
SF3B1 Polyclonal Antibody
For reference only. Please follow the manual included in your kit for instructions.
Catalog Number
Immunofluorescence analysis of U-2 OS cells using SF3B1 Polyclonal Antibody at dilution of 1:100. Blue: DAPI for nuclear staining.
Product Name
SF3B1 Polyclonal Antibody
Catalog Number
RD266583A
Clonality
Polyclonal
Purification Method
Affinity purification
Isotype
IgG
Host
Background
This gene encodes subunit 1 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. The carboxy-terminal two-thirds of subunit 1 have 22 non-identical, tandem HEAT repeats that form rod-like, helical structures. Alternative splicing results in multiple transcript variants encoding different isoforms.
Immunogen Information
Immunogen
Recombinant fusion protein of human SF3B1 (NP_001005526.1).
Gene ID
23451
Swissprot
O75533
Synonyms
SF3B1Hsh155MDSPRP10PRPF10SAP155SF3b155
Applications
Reactivity
, ,
Tested Applications
IF
Conjugation
Unconjugated
Dilution
IF 1:50-1:200
Concentration
1 mg/mL
Storage Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Instructions
Store at -20°C. Avoid freeze / thaw cycles.
Research Areas