SLC10A1 Polyclonal Antibody PE-Cy7 Conjugated

Cat# MBS9463135-0,1mL

Size : 0.1mL

Brand : MyBiosource

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SLC10A1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9463135

MBS9463135 is an antibody targeting SLC10A1. Also known as SLC10A1 Polyclonal Antibody PE-Cy7 Conjugated. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

Product Overview

Online Datasheet in PDF
Product Name
SLC10A1, Polyclonal Antibody
Full Product Name
SLC10A1 Polyclonal Antibody PE-Cy7 Conjugated
Product Gene Name
anti-SLC10A1 antibody
Product Synonym Names
SLC10A1
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Purity/Purification
affinity purified by Protein A
Preparation and Storage
Store at -20 degree C for one year. Avoid repeated freeze/thaw cycles.
Shipped at 4 degree C.
Molecular Weight
38,119 Da
OMIM
182396
3D Structure
ModBase 3D Structure for Q14973
Conjugation
PE-Cy7
Immunogen Type
21-120/349

Product Categories/Family for anti-SLC10A1 antibody

Conjugated Primary Antibodies
Applications Tested/Suitable for anti-SLC10A1 antibody
Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF)
Application Notes for anti-SLC10A1 antibody
FC/FACS: 1:50-200
ICC: 1:50-200
IF: 1:50-200

Other Notes

Small volumes of anti-SLC10A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC10A1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Sodium/bile acid cotransporter
NCBI Official Synonym Full Names
solute carrier family 10 (sodium/bile acid cotransporter), member 1
NCBI Official Symbol
SLC10A1
NCBI Official Synonym Symbols
NTCP
UniProt Protein Name
Sodium/bile acid cotransporter
UniProt Synonym Protein Names
Cell growth-inhibiting gene 29 protein; Na(+)/bile acid cotransporter; Na(+)/taurocholate transport protein; Sodium/taurocholate cotransporting polypeptide; Solute carrier family 10 member 1
Protein Family
Sodium/bile acid cotransporter
UniProt Gene Name
SLC10A1
UniProt Synonym Gene Names
NTCP
UniProt Entry Name
NTCP_HUMAN
NCBI Protein Information
sodium/bile acid cotransporter; growth-inhibiting protein 29; Na(+)/bile acid cotransporter; sodium/taurocholate cotransporter; solute carrier family 10 member 1; Na(+)/taurocholate transport protein; cell growth-inhibiting gene 29 protein; Na/taurocholat

NCBI Summary for SLC10A1

The protein encoded by this gene belongs to the sodium/bile acid cotransporter family, which are integral membrane glycoproteins that participate in the enterohepatic circulation of bile acids. Two homologous transporters are involved in the reabsorption of bile acids; the ileal sodium/bile acid cotransporter with an apical cell localization that absorbs bile acids from the intestinal lumen, bile duct and kidney, and the liver-specific sodium/bile acid cotransporter, represented by this protein, that is found in the basolateral membranes of hepatocytes. Bile acids are the catabolic product of cholesterol metabolism, hence this protein is important for cholesterol homeostasis. [provided by RefSeq, Oct 2011]
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UniProt Comments for SLC10A1

NTCP: The hepatic sodium/bile acid uptake system exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium. Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Transporter

Chromosomal Location of Human Ortholog: 14q24.1

Cellular Component: integral to plasma membrane; basolateral plasma membrane; plasma membrane

Molecular Function: bile acid:sodium symporter activity

Biological Process: bile acid and bile salt transport; bile acid metabolic process; transport; sodium ion transport; transmembrane transport
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SLC10A1 antibody

 Reference Product  PubMed Publications
 ABCB11 antibody  >23 publications with SLC10A1 and ABCB11
 SLCO1B3 antibody  >7 publications with SLC10A1 and SLCO1B3
 SLCO1B1 antibody  >7 publications with SLC10A1 and SLCO1B1
 ABCC3 antibody  >7 publications with SLC10A1 and ABCC3
 SLCO4A1 antibody  >2 publications with SLC10A1 and SLCO4A1
 SLC10A7 antibody  >2 publications with SLC10A1 and SLC10A7
 NR1H4 antibody  >2 publications with SLC10A1 and NR1H4

Pathways associated with anti-SLC10A1 antibody

 Products by Pathway  Pathway Diagram
 Bile Acid And Bile Salt Metabolism Pathway antibodies  Bile Acid And Bile Salt Metabolism Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Drug Induction Of Bile Acid Pathway antibodies  Drug Induction Of Bile Acid Pathway Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Recycling Of Bile Acids And Salts Pathway antibodies  Recycling Of Bile Acids And Salts Pathway Diagram

Diseases associated with anti-SLC10A1 antibody

 Disease Name  Pubmed Publications
 Liver Diseases Antibodies  >15 publications with SLC10A1 and Liver Diseases
 Cholestasis Antibodies  >13 publications with SLC10A1 and Cholestasis
 Liver Neoplasms Antibodies  >5 publications with SLC10A1 and Liver Neoplasms
 Hepatitis Antibodies  >5 publications with SLC10A1 and Hepatitis
 Cholestasis, Intrahepatic Antibodies  >4 publications with SLC10A1 and Cholestasis, Intrahepatic
 Necrosis Antibodies  >4 publications with SLC10A1 and Necrosis
 Inflammation Antibodies  >3 publications with SLC10A1 and Inflammation
 Carcinoma, Hepatocellular Antibodies  >3 publications with SLC10A1 and Carcinoma, Hepatocellular
 Fatty Liver Antibodies  >3 publications with SLC10A1 and Fatty Liver
 Drug-Induced Liver Injury Antibodies  >3 publications with SLC10A1 and Drug-Induced Liver Injury

Organs/Tissues associated with anti-SLC10A1 antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >53 publications with SLC10A1 and Liver
 Intestine Antibodies  >9 publications with SLC10A1 and Intestine
 Kidney Antibodies  >7 publications with SLC10A1 and Kidney
 Brain Antibodies  >6 publications with SLC10A1 and Brain
 Muscle Antibodies  >1 publications with SLC10A1 and Muscle