SP3/4 Antibody

Cat# MBS8581997-0,1mL-Biotin

Size : 0.1mL(Biotin)

Brand : MyBiosource

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SP3/4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8581997

MBS8581997 is an antibody targeting SP3/4. Also known as SP3/4 Antibody. Reactive in Human, Mouse, Chicken, Zebrafish. Host: Rabbit. Rabbit polyclonal antibody to SP3/4 More details

Product Overview

Online Datasheet in PDF
Product Name
SP3/4, Polyclonal Antibody
Full Product Name
SP3/4 Antibody
Product Gene Name
anti-SP3/4 antibody
Product Synonym Gene Name
SP3, SP4
Product Synonym Names
SP3; Transcription factor Sp3; SPR-2; SP4; Transcription factor Sp4; SPR-1
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Chicken, Zebrafish
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of SP3/4 protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Molecular Weight
76,814 Da
OMIM
601804
3D Structure
ModBase 3D Structure for Q02447
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human SP3/4. The exact sequence is proprietary.

Product Categories/Family for anti-SP3/4 antibody

Primary Antibody
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-SP3/4 antibody
Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
Application Notes for anti-SP3/4 antibody
WB: 1:500-1:1000
IHC: 1:50-1:200

Other Notes

Small volumes of anti-SP3/4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SP3/4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
transcription factor Sp3 isoform 2
NCBI Official Synonym Full Names
Sp3 transcription factor
NCBI Official Symbol
SP3
NCBI Official Synonym Symbols
SPR2
UniProt Protein Name
Transcription factor Sp3
UniProt Synonym Protein Names
SPR-2
UniProt Gene Name
SP3
UniProt Entry Name
SP3_HUMAN
NCBI Protein Information
transcription factor Sp3

NCBI Summary for SP3/4

This gene belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes. This protein contains a zinc finger DNA-binding domain and several transactivation domains, and has been reported to function as a bifunctional transcription factor that either stimulates or represses the transcription of numerous genes. Transcript variants encoding different isoforms have been described for this gene, and one has been reported to initiate translation from a non-AUG (AUA) start codon. Additional isoforms, resulting from the use of alternate downstream translation initiation sites, have also been noted. A related pseudogene has been identified on chromosome 13. [provided by RefSeq, Feb 2010]
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UniProt Comments for SP3/4

Transcriptional factor that can act as an activator or repressor depending on isoform and/or post-translational modifications. Binds to GT and GC boxes promoter elements. Competes with SP1 for the GC-box promoters. Weak activator of transcription but can activate a number of genes involved in different processes such as cell-cycle regulation, hormone-induction and house-keeping.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SP3/4 antibody

 Reference Product  PubMed Publications
 SP1 antibody  >1305 publications with SP3/4 and SP1
 CDKN1A antibody  >44 publications with SP3/4 and CDKN1A
 HDAC1 antibody  >34 publications with SP3/4 and HDAC1
 HDAC2 antibody  >22 publications with SP3/4 and HDAC2
 SMAD3 antibody  >17 publications with SP3/4 and SMAD3
 TP53 antibody  >7 publications with SP3/4 and TP53
 EP300 antibody  >3 publications with SP3/4 and EP300
 NFATC1 antibody  >2 publications with SP3/4 and NFATC1
 ESR1 antibody  >1 publications with SP3/4 and ESR1

Pathways associated with anti-SP3/4 antibody

 Products by Pathway  Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Post-translational Protein Modification Pathway antibodies  Post-translational Protein Modification Pathway Diagram
 Regulation Of Telomerase Pathway antibodies  Regulation Of Telomerase Pathway Diagram
 SIDS Susceptibility Pathways antibodies  SIDS Susceptibility Pathways Diagram
 SUMO E3 Ligases SUMOylate Target Proteins Pathway antibodies  SUMO E3 Ligases SUMOylate Target Proteins Pathway Diagram
 SUMOylation Pathway antibodies  SUMOylation Pathway Diagram
 SUMOylation Of Transcription Factors Pathway antibodies  SUMOylation Of Transcription Factors Pathway Diagram
 Selenium Metabolism And Selenoproteins Pathway antibodies  Selenium Metabolism And Selenoproteins Pathway Diagram

Diseases associated with anti-SP3/4 antibody

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >58 publications with SP3/4 and Breast Neoplasms
 Nervous System Diseases Antibodies  >49 publications with SP3/4 and Nervous System Diseases
 Necrosis Antibodies  >40 publications with SP3/4 and Necrosis
 Liver Diseases Antibodies  >37 publications with SP3/4 and Liver Diseases
 Inflammation Antibodies  >32 publications with SP3/4 and Inflammation
 Liver Neoplasms Antibodies  >28 publications with SP3/4 and Liver Neoplasms
 Neoplasms, Experimental Antibodies  >27 publications with SP3/4 and Neoplasms, Experimental
 Fibrosis Antibodies  >24 publications with SP3/4 and Fibrosis
 Carcinoma, Hepatocellular Antibodies  >23 publications with SP3/4 and Carcinoma, Hepatocellular
 Pancreatic Neoplasms Antibodies  >22 publications with SP3/4 and Pancreatic Neoplasms

Organs/Tissues associated with anti-SP3/4 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >160 publications with SP3/4 and Blood
 Brain Antibodies  >108 publications with SP3/4 and Brain
 Vascular Antibodies  >107 publications with SP3/4 and Vascular
 Liver Antibodies  >101 publications with SP3/4 and Liver
 Muscle Antibodies  >99 publications with SP3/4 and Muscle
 Lung Antibodies  >93 publications with SP3/4 and Lung
 Heart Antibodies  >54 publications with SP3/4 and Heart
 Skin Antibodies  >53 publications with SP3/4 and Skin
 Embryonic Tissue Antibodies  >48 publications with SP3/4 and Embryonic Tissue
 Kidney Antibodies  >45 publications with SP3/4 and Kidney