SRR siRNA (Rat)
Cat# MBS828570-15nmol
Size : 15nmol
Brand : MyBiosource
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Phone : +1 850 650 7790
SRR siRNA – Serine Racemase (Rat)
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS828570MBS828570 is an siRNA targeting SRR. Also known as SRR siRNA (Rat). Reactive in Rat. Host: Synthetic. siRNA to inhibit SRR expression using RNA interference More details
Product Overview
Online Datasheet in PDFProduct Name
SRR, siRNA
Full Product Name
SRR siRNA (Rat)
Product Gene Name
SRR sirna
Product Synonym Names
Serine racemase; D-serine ammonia-lyase; D-serine dehydratase; L-serine ammonia-lyase; L-serine dehydratase
Host
Synthetic
Species Reactivity
Rat
Form/Format
Lyophilized powder
Purity/Purification
> 97%
Specificity
SRR siRNA (Rat) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Molecular Weight
35,693 Da
Negative Control
siRNA Negative Control (Catalog# MBS8241404) is a non-targeting 21 nt siRNA recommended as a negative control for experiments using targeted siRNA transfection.
Quality Control
Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
Directions for Use
We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
Components
We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of rat SRR gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
Applications Tested/Suitable for SRR sirna
RNA Interference (RNAi)
Other Notes
Small volumes of SRR sirna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for SRR. It may not necessarily be applicable to this product.
NCBI Official Full Name
serine racemase
NCBI Official Synonym Full Names
serine racemase
NCBI Official Symbol
Srr
UniProt Protein Name
Serine racemase
UniProt Synonym Protein Names
D-serine ammonia-lyase; D-serine dehydratase; L-serine ammonia-lyase; L-serine dehydratase
Protein Family
Probable serine racemase
UniProt Gene Name
Srr
UniProt Entry Name
SRR_RAT
NCBI Protein Information
serine racemase
NCBI Summary for SRR
catalyzes the conversion of L-serine to D-serine [RGD, Feb 2006]
UniProt Comments for SRR
SRR: Catalyzes the synthesis of D-serine from L-serine. D- serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine. Belongs to the serine/threonine dehydratase family.
Protein type: EC 5.1.1.18; Isomerase; Amino Acid Metabolism - glycine, serine and threonine; EC 4.3.1.18; EC 4.3.1.17
Show more Protein type: EC 5.1.1.18; Isomerase; Amino Acid Metabolism - glycine, serine and threonine; EC 4.3.1.18; EC 4.3.1.17
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with SRR sirna
| Reference Product | PubMed Publications |
|---|---|
| Shmt1 sirna | >3 publications with SRR and Shmt1 |
| Sds sirna | >1 publications with SRR and Sds |
Pathways associated with SRR sirna
| Products by Pathway | Pathway Diagram |
|---|---|
| Glycine, Serine And Threonine Metabolism Pathway antibodies | Glycine, Serine And Threonine Metabolism Pathway Diagram |
| Glycine, Serine And Threonine Metabolism Pathway antibodies | Glycine, Serine And Threonine Metabolism Pathway Diagram |
Diseases associated with SRR sirna
| Disease Name | Pubmed Publications |
|---|---|
| Brain Diseases Antibodies | >21 publications with SRR and Brain Diseases |
| Hypertension Antibodies | >16 publications with SRR and Hypertension |
| Liver Diseases Antibodies | >16 publications with SRR and Liver Diseases |
| Genital Diseases, Male Antibodies | >15 publications with SRR and Genital Diseases, Male |
| Liver Neoplasms Antibodies | >14 publications with SRR and Liver Neoplasms |
| Hepatitis Antibodies | >14 publications with SRR and Hepatitis |
| Disease Models, Animal Antibodies | >13 publications with SRR and Disease Models, Animal |
| Infertility, Male Antibodies | >9 publications with SRR and Infertility, Male |
| Kidney Diseases Antibodies | >9 publications with SRR and Kidney Diseases |
| Carcinoma, Hepatocellular Antibodies | >5 publications with SRR and Carcinoma, Hepatocellular |
Organs/Tissues associated with SRR sirna
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Brain Antibodies | >54 publications with SRR and Brain |
| Liver Antibodies | >44 publications with SRR and Liver |
| Kidney Antibodies | >36 publications with SRR and Kidney |
| Colon Antibodies | >9 publications with SRR and Colon |
| Testis Antibodies | >8 publications with SRR and Testis |
| Spleen Antibodies | >1 publications with SRR and Spleen |
| Dorsal Root Ganglion Antibodies | >1 publications with SRR and Dorsal Root Ganglion |