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> SYNGAP1 Protein, Human, Recombinant (His)

SYNGAP1 Protein, Human, Recombinant (His)

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Cat# NB-64-50670-100ug

Size : 100ug

Brand : Neo Biotech

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Phone : +1 850 650 7790

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SYNGAP1 Protein, Human, Recombinant (His)

(Synonyms: SYNGAP1, Synaptic Ras GTPase-activating protein 1 (Synaptic Ras-GAP 1), Ras/Rap GTPase-activating protein SynGAP, Neuronal RasGAP, KIAA1938) Copy Product Info

Synonyms: SYNGAP1, Synaptic Ras GTPase-activating protein 1 (Synaptic Ras-GAP 1), Ras/Rap GTPase-activating protein SynGAP, Neuronal RasGAP, KIAA1938

Catalog No. TMPH-01997 Copy Product Info
SYNGAP1 Protein, Human, Recombinant (His) is expressed in E. coli.
For research use only—not for human use. No sales to individuals. Use as intended only.

Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
SYNGAP1 Protein, Human, Recombinant (His) is expressed in E. coli.
Species
Human
Expression System
E. coli
TagN-6xHis
Accession NumberQ96PV0
Amino AcidMPHLSADIESAHIEREEYKLKEYSKSMDESRLDRVKEYEEEIHSLKERLHMSNRKLEEYERRLLSQEEQTSKILMQYQARLEQSEKRLRQQQAEKDSQIKSIIGRLMLVEEELRRDHPAMAEPLPEPKKRLLDAQERQLPPLGPTNPRVTLAPPWNGLAPPAPPPPPRLQITENGEFRNTADH
Construction1161-1343 aa
Protein Purity
> 90% as determined by SDS-PAGE.
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationTris-based buffer, 50% glycerol
ReconstitutionA Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
SynonymsSYNGAP1, Synaptic Ras GTPase-activating protein 1 (Synaptic Ras-GAP 1), Ras/Rap GTPase-activating protein SynGAP, Neuronal RasGAP, KIAA1938
Research Background
Major constituent of the PSD essential for postsynaptic signaling. Inhibitory regulator of the Ras-cAMP pathway. Member of the NMDAR signaling complex in excitatory synapses, it may play a role in NMDAR-dependent control of AMPAR potentiation, AMPAR membrane trafficking and synaptic plasticity. Regulates AMPAR-mediated miniature excitatory postsynaptic currents. Exhibits dual GTPase-activating specificity for Ras and Rap. May be involved in certain forms of brain injury, leading to long-term learning and memory deficits.
Chemical Properties
Molecular Weight25.5 kDa (predicted)
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Keywords

SYNGAP 1Synaptic Ras-GAP1Synaptic Ras-GAP 1KIAA 1938
Related Tags: SYNGAP1 Protein, Human, Recombinant (His) chemical structure | SYNGAP1 Protein, Human, Recombinant (His) molecular weight