Syntaxin Antibody
Cat# bsm-70277M
Size : 100uL
Brand : Bioss
Contact local distributor :
Phone : +1 850 650 7790
Applications
Reactivity
| Overview | |
| Catalog # | bsm-70277M |
| Product Name | Syntaxin Antibody |
| Applications | WB, IHC |
| Specificity | Specific for endogenous levels of the ~36 kDa syntaxin protein. The antibody has also been used for immunohistochemistry on formalin fixed, vibratome sections. *Does not work on paraffin sections. |
| Reactivity | Human, Rat, Pig, Hamster |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Mouse |
| Source | Synaptic immunoprecipitate (crude) from human brain. |
| Clonality | Monoclonal |
| Clone # | SP8 |
| Isotype | IgG1 |
| Concentration | Lot Dependent |
| Purification | Purified by Protein G. |
| Storage Buffer | 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 g per ml BSA and 50% glycerol. |
| Storage Condition | Storage at -20C is recommended, as aliquots may be taken without freeze/thawing due to presence of 50% glycerol. Stable for at least 1 year at -20C. |
| Target | |
| Gene ID | 6804 |
| Swiss Prot | Q16623 |
| Synonyms | HPC 1 antibody, Neuron specific antigen HPC1 antibody, Neuron-specific antigen HPC-1 antibody, OTTHUMP00000174615 antibody, OTTHUMP00000174616 antibody, OTTHUMP00000174617 antibody, OTTHUMP00000174618 antibody, P35-1 antibody, STX1 antibody, STX1A antibody, STX1A_HUMAN antibody, SYN1A antibody, Syntaxin 1A (brain) antibody, Syntaxin 1A brain antibody, Syntaxin-1A antibody |
| Background | Syntaxins are a family of proteins involved in the docking of synaptic vesicles with the plasma membrane. Syntaxin, along with synaptobrevin and SNAP-25, forms the SNARE complex which mediates synaptic vesicle fusion and exocytosis. Binding of Munc18-1 to the N-terminus of syntaxin 1 has been demonstrated to be essential for exocytic membrane fusion (Khvotchev et al., 2007). Decreased levels of phosphorylated syntaxin 1 in the prefrontal cortex have recently been correlated with schizophrenia (Castillo et al., 2010). |
| Application Dilution | |
| WB | 1:300-5000 |
| IHC | |