TAU Antibody
Cat# MBS8582667-0,1mL-Biotin
Size : 0.1mL(Biotin)
Brand : MyBiosource
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Phone : +1 850 650 7790
TAU Antibody – Rabbit Polyclonal
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8582667MBS8582667 is an antibody targeting TAU. Also known as TAU Antibody. Reactive in Human, Mouse, Rat, Bovine, Pig, Sheep. Host: Rabbit. Rabbit polyclonal antibody to TAU More details
Product Overview
Online Datasheet in PDFProduct Name
TAU, Polyclonal Antibody
Full Product Name
TAU Antibody
Product Gene Name
anti-TAU antibody
Product Synonym Gene Name
MAPT
Product Synonym Names
MAPTL; MTBT1; TAU; Microtubule-associated protein tau; Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Bovine, Pig, Sheep
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH7.3, 30% glycerol, and 0.01% sodium azide.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Specificity
Recognizes endogenous levels of TAU protein.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.
Molecular Weight
78,928 Da
Chromosome Location
Chromosome: 17; NC_000017.10 (43971748..44105700). Location: 17q21.1
OMIM
157140
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human TAU. The exact sequence is proprietary.
Product Categories/Family for anti-TAU antibody
Primary Antibody
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TAU antibody
Western Blot (WB)
Application Notes for anti-TAU antibody
WB: 1:500-1:1000
Other Notes
Small volumes of anti-TAU antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for TAU. It may not necessarily be applicable to this product.
NCBI Official Full Name
microtubule-associated protein tau isoform 6
NCBI Official Synonym Full Names
microtubule-associated protein tau
NCBI Official Symbol
MAPT
NCBI Official Synonym Symbols
TAU; MSTD; PPND; DDPAC; MAPTL; MTBT1; MTBT2; FTDP-17
UniProt Protein Name
Microtubule-associated protein tau
UniProt Synonym Protein Names
Neurofibrillary tangle protein; Paired helical filament-tau
Protein Family
Tau/kappa-theraphotoxin
UniProt Gene Name
MAPT
UniProt Synonym Gene Names
MAPTL; MTBT1; TAU; PHF-tau
UniProt Entry Name
TAU_HUMAN
NCBI Protein Information
microtubule-associated protein tau; PHF-tau; paired helical filament-tau; neurofibrillary tangle protein; microtubule-associated protein tau, isoform 4; G protein beta1/gamma2 subunit-interacting factor 1
NCBI Summary for TAU
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. [provided by RefSeq, Jul 2008]
Show more UniProt Comments for TAU
Tau: a microtubule-associated protein that regulates microtubule assembly and stability. Apparently involved in the establishment and maintenance of neuronal polarity. Mutations can result in several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. Nine differentially spliced isoforms have been described. The short isoforms allow plasticity of the cytoskeleton, whereas the longer isoforms may preferentially play a role in its stabilization.
Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 17q21.1
Cellular Component: microtubule; microtubule associated complex; growth cone; axon; tubulin complex; plasma membrane; axoneme; cytosol
Molecular Function: protein binding; enzyme binding; structural constituent of cytoskeleton; microtubule binding; apolipoprotein binding; protein kinase binding; SH3 domain binding
Biological Process: axon extension; apoptosis; positive regulation of microtubule polymerization; positive regulation of axon extension; axon cargo transport; neuron migration; microtubule cytoskeleton organization and biogenesis; adult walking behavior; regulation of microtubule polymerization; mitochondrion transport along microtubule; negative regulation of intracellular transport; generation of neurons; regulation of autophagy; cell structure disassembly during apoptosis
Disease: Supranuclear Palsy, Progressive, 1; Pick Disease Of Brain; Frontotemporal Dementia; Parkinson-dementia Syndrome; Parkinson Disease, Late-onset; Frontotemporal Lobar Degeneration With Tdp43 Inclusions, Grn-related
Show more Protein type: Cytoskeletal
Chromosomal Location of Human Ortholog: 17q21.1
Cellular Component: microtubule; microtubule associated complex; growth cone; axon; tubulin complex; plasma membrane; axoneme; cytosol
Molecular Function: protein binding; enzyme binding; structural constituent of cytoskeleton; microtubule binding; apolipoprotein binding; protein kinase binding; SH3 domain binding
Biological Process: axon extension; apoptosis; positive regulation of microtubule polymerization; positive regulation of axon extension; axon cargo transport; neuron migration; microtubule cytoskeleton organization and biogenesis; adult walking behavior; regulation of microtubule polymerization; mitochondrion transport along microtubule; negative regulation of intracellular transport; generation of neurons; regulation of autophagy; cell structure disassembly during apoptosis
Disease: Supranuclear Palsy, Progressive, 1; Pick Disease Of Brain; Frontotemporal Dementia; Parkinson-dementia Syndrome; Parkinson Disease, Late-onset; Frontotemporal Lobar Degeneration With Tdp43 Inclusions, Grn-related
Research Articles on TAU
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with anti-TAU antibody
| Reference Product | PubMed Publications |
|---|---|
| APOE antibody | >82 publications with TAU and APOE |
| SNCA antibody | >64 publications with TAU and SNCA |
| PSEN1 antibody | >33 publications with TAU and PSEN1 |
| CDK5 antibody | >24 publications with TAU and CDK5 |
| CASP3 antibody | >17 publications with TAU and CASP3 |
| PPP2CB antibody | >14 publications with TAU and PPP2CB |
| GSK3B antibody | >8 publications with TAU and GSK3B |
| PIN1 antibody | >7 publications with TAU and PIN1 |
| FYN antibody | >6 publications with TAU and FYN |
| CASP6 antibody | >3 publications with TAU and CASP6 |
Pathways associated with anti-TAU antibody
| Products by Pathway | Pathway Diagram |
|---|---|
| Alzheimer's Disease Pathway antibodies | Alzheimer's Disease Pathway Diagram |
| Alzheimer's Disease Pathway antibodies | Alzheimer's Disease Pathway Diagram |
| Alzheimers Disease Pathway antibodies | Alzheimers Disease Pathway Diagram |
| Apoptosis Pathway antibodies | Apoptosis Pathway Diagram |
| Apoptotic Cleavage Of Cellular Proteins Pathway antibodies | Apoptotic Cleavage Of Cellular Proteins Pathway Diagram |
| Apoptotic Execution Phase Pathway antibodies | Apoptotic Execution Phase Pathway Diagram |
| BDNF Signaling Pathway antibodies | BDNF Signaling Pathway Diagram |
| Caspase-mediated Cleavage Of Cytoskeletal Proteins Pathway antibodies | Caspase-mediated Cleavage Of Cytoskeletal Proteins Pathway Diagram |
| IL-2 Signaling Pathway antibodies | IL-2 Signaling Pathway Diagram |
| IL-6 Signaling Pathway antibodies | IL-6 Signaling Pathway Diagram |
Diseases associated with anti-TAU antibody
| Disease Name | Pubmed Publications |
|---|---|
| Nervous System Diseases Antibodies | >855 publications with TAU and Nervous System Diseases |
| Brain Diseases Antibodies | >755 publications with TAU and Brain Diseases |
| Neurodegenerative Diseases Antibodies | >746 publications with TAU and Neurodegenerative Diseases |
| Dementia Antibodies | >706 publications with TAU and Dementia |
| Tauopathies Antibodies | >544 publications with TAU and Tauopathies |
| Alzheimer Disease Antibodies | >402 publications with TAU and Alzheimer Disease |
| Frontotemporal Dementia Antibodies | >305 publications with TAU and Frontotemporal Dementia |
| Movement Disorders Antibodies | >216 publications with TAU and Movement Disorders |
| Parkinsonian Disorders Antibodies | >166 publications with TAU and Parkinsonian Disorders |
| Supranuclear Palsy, Progressive Antibodies | >127 publications with TAU and Supranuclear Palsy, Progressive |
Organs/Tissues associated with anti-TAU antibody
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Brain Antibodies | >561 publications with TAU and Brain |
| Nerve Antibodies | >213 publications with TAU and Nerve |
| Vascular Antibodies | >23 publications with TAU and Vascular |
| Ganglia Antibodies | >22 publications with TAU and Ganglia |
| Muscle Antibodies | >20 publications with TAU and Muscle |
| Eye Antibodies | >9 publications with TAU and Eye |
| Embryonic Tissue Antibodies | >5 publications with TAU and Embryonic Tissue |
| Kidney Antibodies | >5 publications with TAU and Kidney |
| Bone Antibodies | >4 publications with TAU and Bone |
| Thyroid Antibodies | >2 publications with TAU and Thyroid |