Tilfrinib [1600515-49-8]
Cat# T17098-10mg
Size : 10mg
Brand : TargetMol
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Tilfrinib
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Tilfrinib is an effective and selective inhibitor of breast tumor kinase(Brk, IC50 = 3.15 nM) which displays anti-proliferative and anti-tumor activities.
Cas No. 1600515-49-8
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.54%
Appearance:Solid
Color:Yellow
COA HNMR LCMS
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Tilfrinib is an effective and selective inhibitor of breast tumor kinase(Brk, IC50 = 3.15 nM) which displays anti-proliferative and anti-tumor activities. |
| Targets & IC50 | Brk:3.15 nM |
| In vitro | Tilfrinib is against MCF7, HS-578/T, and BT-549 cells with GI50 values of 0.99, 1.02 and 1.58 µM[2]. |
| Molecular Weight | 275.3 |
| Formula | C17H13N3O |
| Cas No. | 1600515-49-8 |
| Smiles | Oc1cccc(Nc2ccnc3[nH]c4ccccc4c23)c1 |
| Relative Density. | 1.421 g/cm3 (Predicted) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 120 mg/mL (435.89 mM), Sonication is recommended.  | |||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween 80+45% Saline: 10 mg/mL (36.32 mM), Solution. 10% DMSO+90% Saline: < 10 mg/mL (36.32 mM), Lower concentrations may be soluble, but exact solubility limit is unknown. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density. | ||||||||||||||||||||||||||||||||||||