TPH2, ID (TPH2, NTPH, Tryptophan 5-hydroxylase 2, Neuronal tryptophan hydroxylase, Tryptophan 5-monooxygenase 2) (FITC)

Cat# 043157-FITC-200ul

Size : 200ul

Brand : US Biological

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Phone : +1 850 650 7790


043157-FITC TPH2, ID (TPH2, NTPH, Tryptophan 5-hydroxylase 2, Neuronal tryptophan hydroxylase, Tryptophan 5-monooxygenase 2) (FITC)

Clone Type
Polyclonal
Host
rabbit
Source
human
Swiss Prot
Q8IWU9
Isotype
IgG
Grade
Affinity Purified
Applications
FLISA IHC WB
Crossreactivity
Hu Mo
Gene #
TPH2
Shipping Temp
Blue Ice
Storage Temp
-20°C

This protein is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control.

Applications:
Suitable for use in FLISA, Western Blot and Immunohistochemistry. Other potential application, though not tested is Direct Flow Cytometry. Other applications have not been tested.

Recommended Dilutions:
Immunohistochemistry: Formalin fixed, paraffin embedded tissues
Optimal dilutions to be determined by the researcher.

Storage and Stability:
Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Note: Applications are based on unconjugated antibody.

Applications
Product Type: Pab|Isotype: IgG|Host: rabbit|Source: human|Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).|Purity: Purified by Protein A and peptide affinity chromatography|Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 168-193 in the central region of human TPH2. Species Sequence Homology: equine and rat|Specificity: Recognizes human TPH2. Species Crossreactivity: mouse||Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Immunogen
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 168-193 in the central region of human TPH2. Species Sequence Homology: equine and rat
Form
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
Purity
Purified by Protein A and peptide affinity chromatography
Specificity
Recognizes human TPH2. Species Crossreactivity: mouse
References
1. Khatua,A.K., et.al., Virology 400 (1), 68-75 (2010). 2. Koning,F.A., et.al., J. Virol. 83 (18), 9474-9485 (2009)

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