Trimethyl chitosan [52349-26-5]
Cat# T84764-10mg
Size : 10mg
Brand : TargetMol
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Trimethyl chitosan
(Synonyms: N,N,N-Trimethylchitosan) Copy Product InfoTrimethyl chitosan is a cationic polymer derived from chemically modified natural chitosan; its water solubility and biocompatibility are enhanced through trimethylation of the amino groups. Trimethyl chitosan targets absorption-enhancing proteins in the tight junctions of intestinal and mucosal epithelial cells, thereby improving drug absorption and stability on mucosal surfaces. Trimethyl chitosan can stimulate the activity that promotes the transmembrane transport of hydrophilic drugs and can be used for drug delivery and the synthesis of nanoparticles.
Cas No. 52349-26-5
For research use only—not for human use. No sales to individuals. Use as intended only.
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Appearance:Solid
Color:White
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Trimethyl chitosan is a cationic polymer derived from chemically modified natural chitosan; its water solubility and biocompatibility are enhanced through trimethylation of the amino groups. Trimethyl chitosan targets absorption-enhancing proteins in the tight junctions of intestinal and mucosal epithelial cells, thereby improving drug absorption and stability on mucosal surfaces. Trimethyl chitosan can stimulate the activity that promotes the transmembrane transport of hydrophilic drugs and can be used for drug delivery and the synthesis of nanoparticles. |
| In vitro | The addition of Trimethyl chitosan (0.05–1.0% (w/v); 2–4 h) to Caco-2 monolayers resulted in a concentration-dependent decrease in transepithelial electrical resistance (TEER) and a significant increase in the transmembrane transport efficiency of 14C-mannitol, with no significant effect on cell viability. [1] |
| Synonyms | N,N,N-Trimethylchitosan |
| Cas No. | 52349-26-5 |
| Storage | Keep away from direct sunlight Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | H2O: 26.66 mg/mL, Sonication is recommended. |