Type II Collagen Antibody
Cat# OASB02740
Size : 0.2mg
Brand : Aviva Systems Biology
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Type II Collagen Antibody (OASB02740)
| Datasheets/Manuals | Printable datasheet for Type II Collagen Antibody (OASB02740) |
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| Tested Species Reactivity | Human |
|---|---|
| Predicted Species Reactivity | Mouse, Rat, Bovine, Chicken, Porcine, Rabbit, Sheep |
| Product Format | Liquid. Borate buffered saline, pH 8.2 |
| Clonality | Polyclonal |
| Host | Goat |
| Conjugation | Unconjugated |
| Application | EM, ICC, IHC-F, IHC-P, IP, WB |
| Additional Information | Description: Pooled antisera from goats hyperimmunized with type II collagen; purified by affinity chromatography on type II collagen covalently linked to agarose; reacts with conformational determinants on type II collagen; cross-adsorbed against Collagen types I, III, IV, V, and VI for minimal reactivity |
| Reconstitution and Storage | Store at 2-8C |
| Immunogen | Type II collagen |
| Concentration | 0.4 mg/mL |
| Specificity | Type II Collagen |
| Gene Symbol | COL2A1 |
|---|---|
| Gene Full Name | collagen type II alpha 1 chain |
| Alias Symbols | AOM, ANFH, SEDC, STL1, COL11A3 |
| NCBI Gene Id | 1280 |
| Protein Name | collagen alpha-1(II) chain |
| Description of Target | This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. |
| Uniprot ID | P02458 |
| Protein Accession # | NP_001835.3 |
| Nucleotide Accession # | NM_001844.4 |