Vasoactive Intestinal Peptide Antagonist, Human ([Ac-Tyr1, D-Phe2l (Growth Hormone Releasing Factor amide 1-29, VIP)
Cat# MBS658624-5x1mg
Size : 5x1mg
Brand : MyBiosource
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Vasoactive Intestinal Peptide Antagonist, Human ([Ac-Tyr1, D-Phe2l (Growth Hormone Releasing Factor Amide 1-29, VIP) Peptide – Synthetic Peptide, ~95%. Purified by HPLC. Purity
For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS658624MBS658624 is a peptide targeting VIPR1. Also known as Vasoactive Intestinal Peptide Antagonist, Human ([Ac-Tyr1, D-Phe2l (Growth Hormone Releasing Factor amide 1-29, VIP). Reactive in Human. Host: Synthetic peptide. Ac-Tyr-D-Phe-Asp-Ala-Ile-Phe-Thr-Asn-Ser- More details
Product Overview
Online Datasheet in PDFProduct Name
Vasoactive Intestinal Peptide Antagonist (VIPR1), Peptide
Full Product Name
Vasoactive Intestinal Peptide Antagonist, Human ([Ac-Tyr1, D-Phe2l (Growth Hormone Releasing Factor amide 1-29, VIP)
Product Gene Name
VIPR1 peptide
Host
Synthetic peptide
Species Reactivity
Human
Form/Format
Supplied as a lyophilized powder.
Purity/Purification
Highly Purified
~95%. Purified by HPLC.
~95%. Purified by HPLC.
Preparation and Storage
Lyophilized powder may be stored at 4 degree C for short-term only. Stable for 12 months at -20 degree C. Reconstitute to nominal volume (see reconstitution instructions for peptides) and store at -20 degree C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
51,547 Da
Chromosome Location
Chromosome: 3; NC_000003.11 (42530791..42579065). Location: 3p22
OMIM
192321
Product Categories/Family for VIPR1 peptide
Molecular Biology; MB-Peptides
Other Notes
Small volumes of VIPR1 peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Additional Details
NCBI/Uniprot data below describe general gene information for VIPR1. It may not necessarily be applicable to this product.
NCBI Official Full Name
vasoactive intestinal polypeptide receptor 1 isoform 1
NCBI Official Synonym Full Names
vasoactive intestinal peptide receptor 1
NCBI Official Symbol
VIPR1
NCBI Official Synonym Symbols
II; HVR1; RDC1; V1RG; VIPR; VIRG; VAPC1; VPAC1; VPAC1R; VIP-R-1; VPCAP1R; PACAP-R2; PACAP-R-2
UniProt Protein Name
Vasoactive intestinal polypeptide receptor 1
UniProt Synonym Protein Names
Pituitary adenylate cyclase-activating polypeptide type II receptor; PACAP type II receptor; PACAP-R-2; PACAP-R2; VPAC1
Protein Family
Vasoactive intestinal polypeptide receptor
UniProt Gene Name
VIPR1
UniProt Synonym Gene Names
VIP-R-1; PACAP type II receptor; PACAP-R-2; PACAP-R2
UniProt Entry Name
VIPR1_HUMAN
NCBI Protein Information
vasoactive intestinal polypeptide receptor 1; VIP receptor, type I; PACAP type II receptor; VIP and PACAP receptor 1; pituitary adenylate cyclase activating polypeptide receptor, type II
NCBI Summary for VIPR1
This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Show more UniProt Comments for VIPR1
Function: This is a receptor for VIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The affinity is VIP = PACAP-27 > PACAP-38. Ref.11
Subcellular location: Cell membrane; Multi-pass membrane protein.
Tissue specificity: In lung, HT-29 colonic epithelial cells, Raji B-lymphoblasts. Lesser extent in brain, heart, kidney, liver and placenta. Not expressed in CD4+ or CD8+ T-cells. Expressed in the T-cell lines HARRIS, HuT 78, Jurkat and SUP-T1, but not in the T-cell lines Peer, MOLT-4, HSB and YT. Ref.11
Sequence similarities: Belongs to the G-protein coupled receptor 2 family.
Show more Subcellular location: Cell membrane; Multi-pass membrane protein.
Tissue specificity: In lung, HT-29 colonic epithelial cells, Raji B-lymphoblasts. Lesser extent in brain, heart, kidney, liver and placenta. Not expressed in CD4+ or CD8+ T-cells. Expressed in the T-cell lines HARRIS, HuT 78, Jurkat and SUP-T1, but not in the T-cell lines Peer, MOLT-4, HSB and YT. Ref.11
Sequence similarities: Belongs to the G-protein coupled receptor 2 family.
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
Product Note
Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
Product PubMed Publications
Products associated with VIPR1 peptide
| Reference Product | PubMed Publications |
|---|---|
| VIP peptide | >81 publications with VIPR1 and VIP |
| ADCYAP1 peptide | >36 publications with VIPR1 and ADCYAP1 |
| GHRH peptide | >2 publications with VIPR1 and GHRH |
| PTH peptide | >1 publications with VIPR1 and PTH |
| CALCA peptide | >1 publications with VIPR1 and CALCA |
Pathways associated with VIPR1 peptide
| Products by Pathway | Pathway Diagram |
|---|---|
| G Alpha (s) Signalling Events Pathway antibodies | G Alpha (s) Signalling Events Pathway Diagram |
| GPCR Downstream Signaling Pathway antibodies | GPCR Downstream Signaling Pathway Diagram |
| GPCRs, Class B Secretin-like Pathway antibodies | GPCRs, Class B Secretin-like Pathway Diagram |
| Glucocorticoid Receptor Regulatory Network Pathway antibodies | Glucocorticoid Receptor Regulatory Network Pathway Diagram |
| Neuroactive Ligand-receptor Interaction Pathway antibodies | Neuroactive Ligand-receptor Interaction Pathway Diagram |
| Neuroactive Ligand-receptor Interaction Pathway antibodies | Neuroactive Ligand-receptor Interaction Pathway Diagram |
| SIDS Susceptibility Pathways antibodies | SIDS Susceptibility Pathways Diagram |
| Signal Transduction Pathway antibodies | Signal Transduction Pathway Diagram |
| Signaling By GPCR Pathway antibodies | Signaling By GPCR Pathway Diagram |
Diseases associated with VIPR1 peptide
| Disease Name | Pubmed Publications |
|---|---|
| Neoplasms Antibodies | >18 publications with VIPR1 and Neoplasms |
| Inflammation Antibodies | >10 publications with VIPR1 and Inflammation |
| Nervous System Diseases Antibodies | >6 publications with VIPR1 and Nervous System Diseases |
| Lung Diseases Antibodies | >6 publications with VIPR1 and Lung Diseases |
| Lung Neoplasms Antibodies | >5 publications with VIPR1 and Lung Neoplasms |
| Breast Neoplasms Antibodies | >4 publications with VIPR1 and Breast Neoplasms |
| Liver Neoplasms Antibodies | >3 publications with VIPR1 and Liver Neoplasms |
| Liver Diseases Antibodies | >3 publications with VIPR1 and Liver Diseases |
| Disease Models, Animal Antibodies | >3 publications with VIPR1 and Disease Models, Animal |
| Necrosis Antibodies | >3 publications with VIPR1 and Necrosis |
Organs/Tissues associated with VIPR1 peptide
| Organ/Tissue Name | Pubmed Publications |
|---|---|
| Blood Antibodies | >23 publications with VIPR1 and Blood |
| Brain Antibodies | >19 publications with VIPR1 and Brain |
| Lung Antibodies | >17 publications with VIPR1 and Lung |
| Intestine Antibodies | >14 publications with VIPR1 and Intestine |
| Muscle Antibodies | >12 publications with VIPR1 and Muscle |
| Prostate Antibodies | >8 publications with VIPR1 and Prostate |
| Pancreas Antibodies | >6 publications with VIPR1 and Pancreas |
| Stomach Antibodies | >5 publications with VIPR1 and Stomach |
| Ovary Antibodies | >5 publications with VIPR1 and Ovary |
| Adrenal Gland Antibodies | >5 publications with VIPR1 and Adrenal Gland |