Medrysone [2668-66-8]

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Référence T0977-25mg

Conditionnement : 25mg

Marque : TargetMol

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Medrysone [2668-66-8]

Medrysone

(Synonyms: Gimeracil, 6α-Methyl-11β-hydroxyprogesterone) Copy Product Info
Medrysone (6α-Methyl-11β-hydroxyprogesterone) is a topical, synthetic glucocorticoid with metabolic, anti-inflammatory and anti-allergic properties. Medrysone exerts its effect by interacting with specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. This results in an induction of the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions is accomplished.
Medrysone
Cas No. 2668-66-8
For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.91%
Color:White
COA HNMR HPLC

Product Introduction

Bioactivity
Description
Medrysone (6α-Methyl-11β-hydroxyprogesterone) is a topical, synthetic glucocorticoid with metabolic, anti-inflammatory and anti-allergic properties. Medrysone exerts its effect by interacting with specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. This results in an induction of the synthesis of certain anti-inflammatory proteins while inhibiting the synthesis of certain inflammatory mediators. Consequently, an overall reduction in chronic inflammation and autoimmune reactions is accomplished.
SynonymsGimeracil, 6α-Methyl-11β-hydroxyprogesterone
Chemical Properties
Molecular Weight344.49
FormulaC22H32O3
Cas No.2668-66-8
Smiles15[C@@]12CC[C@H](C(C)=O)[C@@]1(C)C[C@H](O)[C@@]1(15)[C@@]2(15)C[C@H](C)C2=CC(=O)CC[C@]12C
Relative Density.1.13g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (145.14 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.9028 mL14.5142 mL29.0284 mL145.1421 mL
5 mM0.5806 mL2.9028 mL5.8057 mL29.0284 mL
10 mM0.2903 mL1.4514 mL2.9028 mL14.5142 mL
20 mM0.1451 mL0.7257 mL1.4514 mL7.2571 mL
50 mM0.0581 mL0.2903 mL0.5806 mL2.9028 mL
100 mM0.0290 mL0.1451 mL0.2903 mL1.4514 mL
Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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