Cell-based assay kits - Phagocytosis

In mammals, phagocytosis by phagocytes (such as macrophages, dendritic cells and neutrophils) is essential for a variety of biological events, including tissue remodeling and the ongoing clearance of dying cells . In addition, phagocytosis formation represents an early and crucial event in the initiation of host defenses against invading pathogens. Phagocytosis comprises a series of events beginning with the binding and recognition of particles on surface receptors, followed by the formation of actin-rich membrane extensions around these particles. Fusion of the membrane extensions leads to the phagosome, which is then evaluated as a phagolysosome. Pathogens contained in the phagolysosome are destroyed by falling pH and hydrolysis. These early events, mediated by the innate immune system, are crucial to host survival. This process enables pathogen-derived molecules to be presented to the cell surface, in what is known as antigen presentation, enabling the induction of acquired immunity.
Phagocytosis can be measured in vitro by estimating the engulfment of a substrate by phagocytic cells. Various substrates can be used, including red blood cells, E. coli and Zymosan particles (levure).

with E. coli substrate

with Zymosan substrate

Frequently Asked Questions (FAQ)

Where can I find phagocytosis products on the Biovalley website?

phagocytosis products are available in this section and can be sorted by product families or sub-categories, such as with Zymosan substrate, with E. coli substrate. You can browse the catalogue tree or use the search bar with a product name, catalogue reference, brand or supplier.

What types of products are available in the phagocytosis category?

The phagocytosis category brings together various product references, consumables, reagents, kits, instruments or laboratory solutions, depending on the relevant product family. The with Zymosan substrate, with E. coli substrate sub-categories allow you to find the products that meet your needs more quickly.

How can I quickly find a phagocytosis product?

To find a phagocytosis product, use the search function by name, product code, supplier, brand or sub-category. You can also browse the product families listed on the page to identify an available product code, an alternative or an equivalent product.

Does Biovalley stock several product codes in the phagocytosis category?

Yes, Biovalley distributes several product references in the phagocytosis category, sourced from specialist suppliers. Depending on the product family, references may vary in terms of format, packaging, brand, supplier, technical specifications or availability.

Can I request a quote for phagocytosis products?

Yes, you can request a quote for phagocytosis products from the product page or by contacting Biovalley (info@biovalley.fr). To help us process your enquiry, please provide, where possible, the product name, catalogue reference, required quantity, the supplier or brand you are looking for, and the country of delivery.

How can I find out if a phagocytosis product is available to order?

The availability of a phagocytosis product depends on the product code, supplier, packaging and country of delivery. For up-to-date information, please check the product details page or contact Biovalley with the product code or name of the product you are looking for.

What should I do if I cannot find the phagocytosis product I am looking for?

If the phagocytosis product you are looking for does not appear in the catalogue, please contact Biovalley with the available information: product name, reference number, supplier, brand, format or packaging. The team will be able to search for the reference number within its network of suppliers or suggest an available alternative.

Are all phagocytosis products available under the same terms and conditions?

No. Ordering, delivery, storage and documentation conditions may vary depending on the product type, the supplier and the applicable regulations. Certain product codes may require specific approval, specialised transport, a safety data sheet or additional information prior to ordering.