Ultra Yield® Flasks are advanced high-aeration shake flask systems engineered to improve microbial culture performance, increase biomass accumulation, and enhance recombinant product yields in research and bioprocess development workflows. Designed for high-density cultivation of microbial systems including Escherichia coli, Pichia pastoris, and other expression hosts, these flasks provide substantially improved oxygen transfer compared with conventional shake flasks through optimized geometry and multi-baffle architecture. Enhanced gas exchange enables prolonged logarithmic growth, improved metabolic performance, and higher volumetric productivity in protein expression, plasmid production, strain screening, and microbial process optimization workflows.

Utility of Ultra Yield® Flasks

• Support high-cell-density microbial cultivation for recombinant protein expression and plasmid DNA production workflows.
• Enable scalable shake flask-based process development from early screening to larger culture volumes.
• Improve oxygen transfer and culture performance for aerobic microorganisms and high-metabolic-demand expression systems.
• Suitable for microbial fermentation, synthetic biology, metabolic engineering, and upstream bioprocess optimization.

Key Features

• Up to 10× greater aeration versus traditional shake flasks through optimized six-baffle geometry and enhanced gas exchange.
• Increased protein, biomass, and DNA yields through reduced oxygen limitation and improved culture conditions.
• Sterile, autoclavable polypropylene construction with optional single-use workflows.
• Available in scalable formats from 125 mL to 2.5 L while remaining compatible with standard shaker platforms and flask clamps.