Reagents and instruments for immunology, cell biology and molecular biology.
 
Human Cardiac RNA

Human Cardiac RNA

Human Cardiac RNA consists of RNA extracted from human cardiac tissue and provides a molecular representation of gene expression within the sampled heart tissue. Depending on the extraction method, it can include protein-coding transcripts and non-coding RNA species such as microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and other regulatory RNAs involved in cardiac biology, tissue homeostasis, remodeling, and cardiovascular disease.

Human cardiac RNA is used for targeted and transcriptome-wide gene-expression studies, including RT-qPCR, RNA sequencing (RNA-seq), transcriptome profiling, differential gene-expression analysis, and non-coding RNA research. Bulk cardiac RNA represents the combined RNA profile of multiple cellular populations present in the sampled tissue. Consequently, cell-type-specific expression patterns may require complementary single-cell or single-nucleus RNA-sequencing approaches.

Key Features

  • Representative Cardiac Transcriptome : Provides a molecular representation of gene expression within the sampled human cardiac tissue.

  • Broad RNA Composition : Suitable for analysis of mRNA and, when preserved by the extraction method, miRNA, lncRNA, and other RNA species.

  • Cardiovascular Research Compatibility : Applicable to cardiac gene-expression and cardiovascular disease research.

  • Supports Disease-Associated Expression Studies : Enables investigation of myocardial remodeling and disease-associated transcriptional changes.

  • Flexible RNA Analysis : Suitable for targeted and high-throughput RNA analysis, depending on RNA quality and assay requirements.

Applications

  • Cardiac gene-expression profiling.

  • Cardiovascular disease research, including heart failure, cardiomyopathies, myocardial infarction, and cardiac remodeling.

  • RNA biomarker discovery and candidate biomarker validation.

  • Transcriptomic comparison of healthy and diseased cardiac tissue.

  • Non-coding RNA research.

  • Cardiac development and maturation studies using appropriate tissue sources.

  • Validation of RNA-seq findings by RT-qPCR.