Human Genomic DNA is double-stranded DNA isolated from human biological specimens and contains the genetic information of the human nuclear genome. Genomic DNA provides a source of genetic material for studying genome structure, genetic variation, and heritable traits. Adequate DNA purity, concentration, and molecular integrity are important for reproducible molecular genetics and genomic analyses.
Key Features
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Genome-wide genetic information: Supports analysis of coding and non-coding genomic regions, including single-nucleotide variants (SNVs/SNPs), insertions/deletions (indels), and, depending on DNA quality and analytical method, structural variants.
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Molecular integrity: Sufficiently intact and pure genomic DNA supports applications such as PCR, genotyping, sequencing, and DNA archiving.
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Human genetic research: Provides genomic DNA templates for downstream molecular genetics and genome-wide analyses.
Typical Research Applications
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Whole-genome sequencing (WGS) and targeted sequencing.
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PCR and quantitative PCR (qPCR).
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SNP genotyping and genetic variant analysis.
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DNA microarray-based genotyping and genome-wide association studies (GWAS).
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Population genetics, ancestry, and genetic diversity studies.
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Investigation of genetic variation associated with human disease and complex traits.
