Thomson Rapid Clear® Cap is an advanced cell culture clarification solution designed to streamline downstream processing workflows for mammalian and insect cell cultures. Engineered for compatibility with Thomson Optimum Growth® flasks, the Rapid Clear® system enables rapid clarification directly from culture vessels, minimizing handling steps and eliminating many of the bottlenecks associated with conventional centrifugation and multi-stage filtration workflows. This technology supports efficient harvest of high-density cultures while helping maintain sterility and reducing process complexity.

Utility & Applications

Rapid Clear® Caps are ideal for:

• Mammalian cell culture clarification workflows for recombinant protein and biologics production.
• Harvesting CHO, HEK293, hybridoma, transient, and stable cell cultures.
• Small- to mid-scale bioprocessing and process development workflows.
• Downstream preparation prior to protein purification and analytics.
• Reducing manual intervention in cell culture harvest operations.

Key Features

• Clarifies up to ~3 L of culture in under 30 minutes without centrifugation in many workflows.
• Integrated depth filtration with 0.2 μm final pore size for streamlined clarification.
• Compatible with 2.8 L and 5 L Optimum Growth® flasks.
• Direct flask attachment minimizes transfer steps and contamination risks.
• Supports high-density cell cultures while reducing consumable usage by up to 90%.
• Sterile, individually packaged components for aseptic processing environments (SAL 10⁻⁶).