Thomson Optimum Growth® Sampling and Standard Flasks are advanced single-use cell culture vessels designed to enhance mammalian, CHO, HEK293, hybridoma, and insect cell cultivation. Developed for upstream bioprocess development, protein expression, and scale-up workflows, these flasks combine high-efficiency oxygen transfer, scalable formats, and contamination-controlled operation to support modern biopharmaceutical research.
Utility in Cell Culture and Bioprocessing
These flasks are widely used in:
- Cell line development and optimization
- Transient and stable protein expression systems
- Scale-up from microplates to large-volume shaker cultures
- Biotherapeutic protein and antibody production
Sampling variants further enable aseptic, in-shaker sampling, reducing workflow interruptions and maintaining culture integrity without removing caps or transferring vessels outside controlled environments.
Key Features
- Scalable design (125 mL to 7 L) enabling seamless transition across development stages.
- High fill-volume efficiency (40–50%) improving shaker space utilization compared to traditional flasks.
- Proprietary baffled geometry for enhanced aeration and reduced shear stress, supporting higher cell viability and productivity.
- 0.2 µm PTFE vented caps ensuring sterile gas exchange and contamination control.
- Aseptic sampling ports (sampling flasks) allowing direct syringe-based sampling during culture without opening the vessel.
- Standardized shake parameters across all sizes, simplifying scale-up and process reproducibility.
Optimized for consistency, sterility, and scalability, Optimum Growth® flasks provide a robust platform for accelerating cell culture workflows while maintaining high-quality biological output.