RR-11a [1361390-56-8]
Cat# T12769-25mg
Size : 25mg
Brand : TargetMol
Contact local distributor :
Phone : +1 850 650 7790
RR-11a
Copy Product InfoRR-11a is a synthetic enzyme legumain inhibitor. This compound specifically targets and inhibits the activity of legumain, an enzyme implicated in various biological processes. RR-11a's synthetic nature allows for precise modulation of legumain activity, making it a valuable tool in biochemical research and potential therapeutic applications.
Cas No. 1361390-56-8
With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
For research use only—not for human use. No sales to individuals. Use as intended only.
Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | RR-11a is a synthetic enzyme legumain inhibitor. This compound specifically targets and inhibits the activity of legumain, an enzyme implicated in various biological processes. RR-11a's synthetic nature allows for precise modulation of legumain activity, making it a valuable tool in biochemical research and potential therapeutic applications. |
| Targets & IC50 | Legumain:31-55 nM (IC50) |
| In vitro | Legumain-targeted nanoparticles coupled with RR-11a demonstrate substantial ligand-receptor affinity, thereby enabling enhanced penetration and uptake within solid tumors by tumor cells. |
| In vivo | Tumor-bearing mice treated with RR-11a-coupled NPs encapsulating doxorubicin results in improved tumor selectivity and drug sensitivity, It completely inhibits tumor growth. |
| Molecular Weight | 560.51 |
| Formula | C24H28N6O10 |
| Cas No. | 1361390-56-8 |
| Smiles | O(C(/C=C/C(N(NC([C@@H](NC([C@@H](NC(OCC1=CC=CC=C1)=O)C)=O)C)=O)CC(N)=O)=O)=O)N2C(=O)CCC2=O |
| Relative Density. | no data available |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |