Reagents and instruments for immunology, cell biology and molecular biology.
 
Cleavage Under Targets and Tagmentation assays

Cleavage Under Targets and Tagmentation assays

CUT&Tag (Cleavage Under Targets and Tagmentation) is a highly sensitive, low-input technique for profiling protein–DNA interactions and chromatin modifications with exceptional resolution and minimal background noise. The method relies on antibody-directed recruitment of a protein A/G–Tn5 transposase fusion protein, enabling in situ tagmentation and the direct generation of sequencing-ready DNA fragments from intact nuclei or permeabilized cells without the need for chromatin shearing or immunoprecipitation.

Key Advantages

  • High Sensitivity and Low Input: Suitable for experiments using only hundreds to thousands of cells, including precious clinical and limited biological samples.
  • High Signal-to-Noise Ratio: Delivers reduced nonspecific background and highly accurate peak identification for robust epigenomic analysis.
  • Broad Sample Compatibility: Applicable to primary cells, sorted cell populations, frozen specimens, lightly fixed samples, and single-cell workflows.
  • Streamlined Workflow: Minimizes handling steps, reducing sample loss, experimental variability, and processing time.

Applications

  • Epigenomic mapping of histone modifications and transcription factor binding sites.
  • Comparative chromatin profiling across cell types, treatments, developmental stages, or disease conditions.
  • Low-input epigenetic studies and clinical sample analysis.
  • Single-cell and indexed CUT&Tag applications for cell-type-specific chromatin landscape characterization.

Frequently Asked Questions (FAQ)

How can I quickly find a cut&tag assays product?

To find a cut&tag assays product, use the search function by name, product code, supplier, brand or sub-category. You can also browse the product families listed on the page to identify an available product code, an alternative or an equivalent product.

Does Biovalley stock several product codes in the cut&tag assays category?

Yes, Biovalley distributes several product references in the cut&tag assays category, sourced from specialist suppliers. Depending on the product family, references may vary in terms of format, packaging, brand, supplier, technical specifications or availability.

Can I request a quote for cut&tag assays products?

Yes, you can request a quote for cut&tag assays products from the product page or by contacting Biovalley (info@biovalley.fr). To help us process your enquiry, please provide, where possible, the product name, catalogue reference, required quantity, the supplier or brand you are looking for, and the country of delivery.

How can I find out if a cut&tag assays product is available to order?

The availability of a cut&tag assays product depends on the product code, supplier, packaging and country of delivery. For up-to-date information, please check the product details page or contact Biovalley with the product code or name of the product you are looking for.

What should I do if I cannot find the cut&tag assays product I am looking for?

If the cut&tag assays product you are looking for does not appear in the catalogue, please contact Biovalley with the available information: product name, reference number, supplier, brand, format or packaging. The team will be able to search for the reference number within its network of suppliers or suggest an available alternative.

Are all cut&tag assays products available under the same terms and conditions?

No. Ordering, delivery, storage and documentation conditions may vary depending on the product type, the supplier and the applicable regulations. Certain product codes may require specific approval, specialised transport, a safety data sheet or additional information prior to ordering.

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