Reagents and instruments for immunology, cell biology and molecular biology.
 
DNA methyltransferase 3 beta

DNA methyltransferase 3 beta

DNA methyltransferase 3 beta (DNMT3B) is a de novo DNA methyltransferase responsible for establishing new CpG methylation patterns during embryonic development, cellular differentiation, and epigenetic regulation. Recombinant DNMT3B proteins are indispensable tools for investigating DNA methylation mechanisms, characterizing enzyme activity, screening epigenetic inhibitors, and validating antibody performance.

Recombinant Protein Formats

DNMT3B is available as full-length proteins, catalytic C-terminal domains, regulatory PWWP and ADD domains, isoform-specific variants, or physiologically relevant DNMT3B:DNMT3L complexes. Expression in insect or mammalian cells provides optimal folding and post-translational modifications, while E. coli offers economical production of isolated domains.

Quality and Research Applications

  • Quality Control: Sequence verification, purity, enzymatic activity, oligomeric state, endotoxin level, and Certificate of Analysis ensure reliable performance.
  • Applications: Widely used for enzyme kinetics, inhibitor screening, structural biology, DNA and histone binding studies, epigenetic research, and antibody validation using activity-qualified recombinant proteins.

Frequently Asked Questions (FAQ)

How can I quickly find a dnmt3b product?

To find a dnmt3b product, use the search function by name, product code, supplier, brand or sub-category. You can also browse the product families listed on the page to identify an available product code, an alternative or an equivalent product.

Does Biovalley stock several product codes in the dnmt3b category?

Yes, Biovalley distributes several product references in the dnmt3b category, sourced from specialist suppliers. Depending on the product family, references may vary in terms of format, packaging, brand, supplier, technical specifications or availability.

Can I request a quote for dnmt3b products?

Yes, you can request a quote for dnmt3b products from the product page or by contacting Biovalley (info@biovalley.fr). To help us process your enquiry, please provide, where possible, the product name, catalogue reference, required quantity, the supplier or brand you are looking for, and the country of delivery.

How can I find out if a dnmt3b product is available to order?

The availability of a dnmt3b product depends on the product code, supplier, packaging and country of delivery. For up-to-date information, please check the product details page or contact Biovalley with the product code or name of the product you are looking for.

What should I do if I cannot find the dnmt3b product I am looking for?

If the dnmt3b product you are looking for does not appear in the catalogue, please contact Biovalley with the available information: product name, reference number, supplier, brand, format or packaging. The team will be able to search for the reference number within its network of suppliers or suggest an available alternative.

Are all dnmt3b products available under the same terms and conditions?

No. Ordering, delivery, storage and documentation conditions may vary depending on the product type, the supplier and the applicable regulations. Certain product codes may require specific approval, specialised transport, a safety data sheet or additional information prior to ordering.

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