Reagents and instruments for immunology, cell biology and molecular biology.
 
Recombinant DNMT3A

Recombinant DNMT3A

Recombinant DNMT3A is the principal de novo DNA methyltransferase used to investigate epigenetic regulation, DNA methylation establishment, enzyme activity, and inhibitor discovery. Commercially available as full-length protein or as individual functional domains, recombinant DNMT3A supports biochemical, structural, and chromatin interaction studies while providing a reliable platform for understanding methylation-dependent gene regulation.

Expression Systems & Quality

Full-length proteins are commonly expressed in insect or mammalian cells to preserve native folding and post-translational modifications, whereas isolated domains are frequently produced in E. coli. Product quality should be verified by purity, sequence confirmation, enzymatic activity, oligomeric state, endotoxin level, and recommended storage conditions.

Research Applications

  • Epigenetic studies: DNA methylation and chromatin regulation.
  • Drug discovery: Methyltransferase activity assays and inhibitor screening.
  • Structural biology: Cryo-EM, X-ray crystallography, and protein interaction analyses.
  • Biophysical assays: DNA, histone, and DNMT3L binding studies using SPR, ITC, and fluorescence-based methods.

Frequently Asked Questions (FAQ)

How can I quickly find a dnmt3a product?

To find a dnmt3a product, use the search function by name, product code, supplier, brand or sub-category. You can also browse the product families listed on the page to identify an available product code, an alternative or an equivalent product.

Does Biovalley stock several product codes in the dnmt3a category?

Yes, Biovalley distributes several product references in the dnmt3a category, sourced from specialist suppliers. Depending on the product family, references may vary in terms of format, packaging, brand, supplier, technical specifications or availability.

Can I request a quote for dnmt3a products?

Yes, you can request a quote for dnmt3a products from the product page or by contacting Biovalley (info@biovalley.fr). To help us process your enquiry, please provide, where possible, the product name, catalogue reference, required quantity, the supplier or brand you are looking for, and the country of delivery.

How can I find out if a dnmt3a product is available to order?

The availability of a dnmt3a product depends on the product code, supplier, packaging and country of delivery. For up-to-date information, please check the product details page or contact Biovalley with the product code or name of the product you are looking for.

What should I do if I cannot find the dnmt3a product I am looking for?

If the dnmt3a product you are looking for does not appear in the catalogue, please contact Biovalley with the available information: product name, reference number, supplier, brand, format or packaging. The team will be able to search for the reference number within its network of suppliers or suggest an available alternative.

Are all dnmt3a products available under the same terms and conditions?

No. Ordering, delivery, storage and documentation conditions may vary depending on the product type, the supplier and the applicable regulations. Certain product codes may require specific approval, specialised transport, a safety data sheet or additional information prior to ordering.

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